HCID 22242594, compound → HCID 22242603, compound

Participants

Reaction Steps

To a solution of 7 (120 mg, 0.2 mmol) in 5 mL of MeOH was added 9 (101 mg, 0.22 mmol). The solution was stirred at room temperature for 33 hours. After concentration, the reaction mixture was purified by flash chromatography (gradient: CH2Cl2/MeOH, 20:1 to 10:1 to 5:1, v/v) to afford 137 mg of impure 8. 1H NMR 400 MHz (CD3OD) d 3.85 (t, J=4.8 Hz, 2H), 3.76–3.52 (m, 32H), 3.42 (m, 4H), 3.14 (t, J=4.8 Hz, 2H), 2.65 (t, J=7.4 Hz, 4H), 1.67 (m, 2H), 1.55 (m, 2H), 1.40–1.18 (br m, 32H).

Provenance & Evidence