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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 891010Generated: October 30, 2026

1-Heptanamine → HCID 69610169, compound

https://huagongshe.com/reaction/891010

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-HeptanamineHCID 8127—
Reactant1-(1,1-Dimethylethyl) 3-ethyl 4-oxo-1,3-piperidinedicarboxylateHCID 6420876—
SolventTolueneHCID 1140—
ProductHCID 69610169HCID 69610169—

Reaction Steps

A solution of 1-tert-butoxycarbonyl-3-ethoxycarbonyl-piperidin-4-one (prepared from 3-ethoxycarbonyl-piperidin-4-one and di-tert-butyl-dicarbonate in dichloromethane and triethylamine) (8.5 g) and heptylamine (3.61 g) in toluene (100 ml) was heated under reflux in a Dean and Stark apparatus for 18 hours and then evaporated to dryness to give an oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07001913B1
Source datasetuspto-grants-2006_02
ORD IDord-9aa7fb4a35054be4a02dfdb0e2d90142
Source noteuspto-grants-2006_02