HuagongsheHuagongshe Chemistry Print Report · For research reference only
m,alpha-Dichlorotoluene → Ethyl 9-(3-chlorobenzyl)-6-nitro-9H-beta-carboline-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | m,alpha-Dichlorotoluene | HCID 12103 | — |
| Reactant | ethyl 6-nitro-9H-beta-carboline-3-carboxylate | HCID 13037332 | — |
| Product | Ethyl 9-(3-chlorobenzyl)-6-nitro-9H-beta-carboline-3-carboxylate | HCID 21883399 | — |
Reaction Steps
The title compound was prepared by alkylation of ethyl 6-nitro-9H-β-carboline-3-carboxylate (prepared according to Settimj, et. al., J. Heterocycl. Chem., 25, 1391–1397 (1988)) with 3-chlorobenzyl chloride in a manner similar to step (a) of example 7. LCMS (APCI, M+H+): 410.1/412.1=3/1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07001912B2 |
| Source dataset | uspto-grants-2006_02 |
| ORD ID | ord-d20e1727ac2045d59427c10924672668 |
| Source note | uspto-grants-2006_02 |