p-Toluenesulfonic acid → HCID 22244657, compound

Participants

Reaction Steps

A mixture of N-{[(2-{4-[4-(4-fluorophenyl)-3,5-dimethyl-1H-pyrazol-1-yl]phenyl}ethyl)amino]carbonyl}-4-methylbenzenesulfonamide (step 5, 146 mg, 0.289 mmol), p-toluenesulfonic acid (55 mg, 0.289 mmol) in acetone (10 ml) and methanol (10 mL) was stirred at room temperature for 1 h. The reaction mixture was evaporated to afford 195 mg of the title compound as white solids: MS (ESI) m/z 507 [M+H]+, 505 [M−H]−.

Provenance & Evidence