4-Ethylbenzenesulfonamide → HCID 22244520, compound

HRID 891089Notes

Reaction equation

[CH3:1][C:2]1[C:6]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)=[C:5]([CH3:13])[N:4]([C:14]2[CH:19]=[CH:18][C:17]([CH2:20][CH2:21][NH:22][C:23](=O)[O:24]C3C=CC=CC=3)=[CH:16][CH:15]=2)[N:3]=1.[CH2:32]([C:34]1[CH:39]=[CH:38][C:37]([S:40]([NH2:43])(=[O:42])=[O:41])=[CH:36][CH:35]=1)[CH3:33]>>[CH3:1][C:2]1[C:6]([C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=2)=[C:5]([CH3:13])[N:4]([C:14]2[CH:15]=[CH:16][C:17]([CH2:20][CH2:21][NH:22][C:23]([NH:43][S:40]([C:37]3[CH:36]=[CH:35][C:34]([CH2:32][CH3:33])=[CH:39][CH:38]=3)(=[O:41])=[O:42])=[O:24])=[CH:18][CH:19]=2)[N:3]=1

Participants

Reactant 2

HCID 2228704-Ethylbenzenesulfonamide

HCID 22244550Phenyl 2-[4-(3,5-dimethyl-4-phenyl-1H-pyrazol-1-yl)phenyl]ethylcarbamate

Product 1

HCID 22244520HCID 22244520, compound

Procedure

The title compound was prepared according to the procedure described in step 2 of Example 22 from phenyl 2-[4-(3,5-dimethyl-4-phenyl-1H-pyrazol-1-yl)phenyl]ethylcarbamate (step 1 of Example 22) and 4-ethylbenzenesulfonamide: 1H-NMR (CDCl3) δ 7.77 (2H, d, J=8.4 Hz), 7.47-7.23 (11H, m), 6.39 (1H, br.s), 3.52-3.45 (2H, m), 2.86 (2H, t, J=6.7 Hz), 2.71 (2H, q, J=7.7 Hz), 2.33 (3H, s), 2.25 (3H, s), 1.25 (3H, t, J=7.7 Hz).

Sources & evidence

ORD record: ord-72dc59deb2df47439d1f144aacc76c16
Source dataset: uspto-grants-2006_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07001917B2

Reaction notes

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