4-(1-Methylethyl)benzenesulfonamide → HCID 22244545, compound

HRID 891090Notes

Reaction equation

HRID 891090 reaction equation
[CH3:1][C:2]1[C:6]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)=[C:5]([CH3:13])[N:4]([C:14]2[CH:19]=[CH:18][C:17]([CH2:20][CH2:21][NH:22][C:23](=O)[O:24]C3C=CC=CC=3)=[CH:16][CH:15]=2)[N:3]=1.[CH3:32][CH:33]([C:35]1[CH:40]=[CH:39][C:38]([S:41]([NH2:44])(=[O:43])=[O:42])=[CH:37][CH:36]=1)[CH3:34]>>[CH3:1][C:2]1[C:6]([C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=2)=[C:5]([CH3:13])[N:4]([C:14]2[CH:15]=[CH:16][C:17]([CH2:20][CH2:21][NH:22][C:23]([NH:44][S:41]([C:38]3[CH:37]=[CH:36][C:35]([CH:33]([CH3:32])[CH3:34])=[CH:40][CH:39]=3)(=[O:43])=[O:42])=[O:24])=[CH:18][CH:19]=2)[N:3]=1

Participants

3

Reactant 2

HCID 2323144-(1-Methylethyl)benzenesulfonamideHCID 22244550Phenyl 2-[4-(3,5-dimethyl-4-phenyl-1H-pyrazol-1-yl)phenyl]ethylcarbamate

Product 1

HCID 22244545HCID 22244545, compound

Procedure

The title compound was prepared according to the procedure described in step 2 of Example 22 from phenyl 2-[4-(3,5-dimethyl-4-phenyl-1H-pyrazol-1-yl)phenyl]ethylcarbamate (step 1 of Example 22) and 4-(1-methylethyl)benzenesulfonamide: 1H-NMR (CDCl3) δ 7.75 (2H, d, J=8.4 Hz), 7.47-7.24 (11H, m), 6.44 (1H, br.s), 3.54-3.47 (2H, m), 3.02-2.84 (3H, m), 2.33 (3H, s), 2.26 (3H, s), 1.25 (6H, d, J=6.9 Hz).

Sources & evidence

ORD record
ord-1a0ad37506064d239b792928fc4b0534
Source dataset
uspto-grants-2006_02
Patent number
US07001917B2

Reaction notes

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