2-Methylbenzenesulfonamide → HCID 10152169, compound

HRID 891096Notes

Reaction equation

[CH3:1][C:2]1[C:6]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)=[C:5]([CH3:13])[N:4]([C:14]2[CH:19]=[CH:18][C:17]([CH2:20][CH2:21][NH:22][C:23](=O)[O:24]C3C=CC=CC=3)=[CH:16][CH:15]=2)[N:3]=1.[CH3:32][C:33]1[CH:38]=[CH:37][CH:36]=[CH:35][C:34]=1[S:39]([NH2:42])(=[O:41])=[O:40]>>[CH3:1][C:2]1[C:6]([C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=2)=[C:5]([CH3:13])[N:4]([C:14]2[CH:15]=[CH:16][C:17]([CH2:20][CH2:21][NH:22][C:23]([NH:42][S:39]([C:34]3[CH:35]=[CH:36][CH:37]=[CH:38][C:33]=3[CH3:32])(=[O:41])=[O:40])=[O:24])=[CH:18][CH:19]=2)[N:3]=1

Participants

Reactant 2

HCID 69242-Methylbenzenesulfonamide

HCID 22244550Phenyl 2-[4-(3,5-dimethyl-4-phenyl-1H-pyrazol-1-yl)phenyl]ethylcarbamate

Product 1

HCID 10152169HCID 10152169, compound

Procedure

The title compound was prepared according to the procedure described in step 2 of Example 22 from phenyl 2-[4-(3,5-dimethyl-4-phenyl-1H-pyrazol-1-yl)phenyl]ethylcarbamate (step 1 of Example 22) and 2-methylbenzenesulfonamide: 1H-NMR (CDCl3) δ 7.93 (1H, d, J=8.3 Hz), 7.50-7.21 (12H, m), 6.29 (1H, br.s), 3.49-3.43 (2H, m), 2.81 (2H, t, J=6.5 Hz), 2.62 (3H, s), 2.33 (3H, s), 2.24 (3H, s).

Sources & evidence

ORD record: ord-7289a7c9bf9645cca032eb86f3fef6b7
Source dataset: uspto-grants-2006_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07001917B2

Reaction notes

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