Pyridine-4-sulfonamide → HCID 22244575, compound

HRID 891105Notes

Reaction equation

HRID 891105 reaction equation
[CH3:1][C:2]1[C:6]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)=[C:5]([CH3:13])[N:4]([C:14]2[CH:19]=[CH:18][C:17]([CH2:20][CH2:21][NH:22][C:23](=[O:31])OC3C=CC=CC=3)=[CH:16][CH:15]=2)[N:3]=1.[N:32]1[CH:37]=[CH:36][C:35]([S:38]([NH2:41])(=[O:40])=[O:39])=[CH:34][CH:33]=1>>[CH3:1][C:2]1[C:6]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)=[C:5]([CH3:13])[N:4]([C:14]2[CH:19]=[CH:18][C:17]([CH2:20][CH2:21][NH:22][C:23]([NH:41][S:38]([C:35]3[CH:36]=[CH:37][N:32]=[CH:33][CH:34]=3)(=[O:40])=[O:39])=[O:31])=[CH:16][CH:15]=2)[N:3]=1

Participants

3

Reactant 2

HCID 12383449Pyridine-4-sulfonamideHCID 22244550Phenyl 2-[4-(3,5-dimethyl-4-phenyl-1H-pyrazol-1-yl)phenyl]ethylcarbamate

Product 1

HCID 22244575HCID 22244575, compound

Procedure

The title compound was prepared according to the procedure described in step 2 of Example 22 from phenyl 2-[4-(3,5-dimethyl-4-phenyl-1H-pyrazol-1-yl)phenyl]ethylcarbamate (step 1 of Example 22) and 4-pyridinesulfonamide (J. Chem. Soc., 1958, 3514: 1H-NMR (CDCl3) δ 8.81 (2H, d, J=5.4 Hz), 7.77 (2H, d, J=5.9 Hz), 7.46-7.18 (9H, m), 6.11 (1H, br.s), 3.44-3.41 (2H, m), 2.84-2.79 (2H, m), 2.31 (3H, s), 2.21 (3H, s).

Sources & evidence

ORD record
ord-6221c01d6faf48f0825df260abaa6aee
Source dataset
uspto-grants-2006_02
Patent number
US07001917B2

Reaction notes

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