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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 891110Generated: October 31, 2026

2,4-Difluorobenzenesulfonamide → N-[({2-[4-(3,5-Dimethyl-4-phenyl-1H-pyrazol-1-yl)phenyl]ethyl}amino)carbonyl]-2,4-difluorobenzenesulfonamide

https://huagongshe.com/reaction/891110

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DifluorobenzenesulfonamideHCID 574964—
ReactantPhenyl 2-[4-(3,5-dimethyl-4-phenyl-1H-pyrazol-1-yl)phenyl]ethylcarbamateHCID 22244550—
ProductN-[({2-[4-(3,5-Dimethyl-4-phenyl-1H-pyrazol-1-yl)phenyl]ethyl}amino)carbonyl]-2,4-difluorobenzenesulfonamideHCID 10128400—

Reaction Steps

The title compound was prepared according to the procedure described in step 1 of Example 42 from phenyl 2-[4-(3,5-dimethyl-4-phenyl-1H-pyrazol-1-yl)phenyl]ethylcarbamate (step 1 of Example 22) and 2,4-difluorobenzenesulfonamide: 1H-NMR (CDCl3) δ 7.98-7.90 (1H, m), 7.47-7.41 (2H, m), 7.35-7.22 (7H, m), 7.07-6.92 (2H, m), 6.16 (1H, br.s), 3.50-3.43 (2H, m), 2.84 (2H, t, J=6.6 Hz), 2.33 (3H, s), 2.23 (3H, s).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07001917B2
Source datasetuspto-grants-2006_02
ORD IDord-4daed609f4064dcb91ffb0ecec291147
Source noteuspto-grants-2006_02