Phenyl 2-[4-(3,5-dimethyl-4-phenyl-1H-pyrazol-1-yl)phenyl]ethylcarbamate → HCID 22244637, compound

HRID 891138Notes

Reaction equation

HRID 891138 reaction equation
[CH3:1][C:2]1[C:6]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)=[C:5]([CH3:13])[N:4]([C:14]2[CH:19]=[CH:18][C:17]([CH2:20][CH2:21][NH:22][C:23](=[O:31])OC3C=CC=CC=3)=[CH:16][CH:15]=2)[N:3]=1.[C:32]1([S:42]([NH2:45])(=[O:44])=[O:43])[CH:37]=[CH:36][C:35]([S:38]([NH2:41])(=[O:40])=[O:39])=[CH:34][CH:33]=1>>[CH3:1][C:2]1[C:6]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)=[C:5]([CH3:13])[N:4]([C:14]2[CH:19]=[CH:18][C:17]([CH2:20][CH2:21][NH:22][C:23]([NH:45][S:42]([C:32]3[CH:33]=[CH:34][C:35]([S:38]([NH2:41])(=[O:40])=[O:39])=[CH:36][CH:37]=3)(=[O:44])=[O:43])=[O:31])=[CH:16][CH:15]=2)[N:3]=1

Participants

3

Reactant 2

HCID 22244550Phenyl 2-[4-(3,5-dimethyl-4-phenyl-1H-pyrazol-1-yl)phenyl]ethylcarbamateHCID 23273948Benzene-1,4-disulfonamide

Product 1

HCID 22244637HCID 22244637, compound

Procedure

The title compound was prepared according to the procedure described in step 2 of Example 22 from phenyl 2-[4-(3,5-dimethyl-4-phenyl-1H-pyrazol-1-yl)phenyl]ethylcarbamate (step 1 of Example 22) and benzene-1,4-disulfonamide: 1H-NMR (DMSO-d6) δ 8.10-8.01 (4H, m), 7.63 (2H, s), 7.48-7.27 (9H, m), 6.62-6.59 (1H, m), 3.28-3.21 (2H, m), 2.73 (21H, t, J=7.2 Hz), 2.27 (3H, s), 2.23 (3H, s).

Sources & evidence

ORD record
ord-df5c9b0668eb4a09b93301020bbe9b9a
Source dataset
uspto-grants-2006_02
Patent number
US07001917B2

Reaction notes

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