HRID891157

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID3090044

1,3-BENZENEDISULFONAMIDE

C6H8N2O4S2

结构：Cc1nn(-c2ccc(CCNC(=O)Oc3ccccc3)cn2)c(C)c1-c1ccccc1

HCID22244603

未命名化合物

PRODUCTS

生成物

结构：Cc1nn(-c2ccc(CCNC(=O)NS(=O)(=O)c3cccc(S(N)(=O)=O)c3)cn2)c(C)c1-c1ccccc1

HCID22244541

未命名化合物

PROCEDURE

实验过程

The title compound was prepared according to the procedure described in step 1 of Example 42 from phenyl 2-[6-(3,5-dimethyl-4-phenyl-1H-pyrazol-1-yl)pyridin-3-yl]ethylcarbamate (step 5 of Example 83) and 1,3-benzenedisulfonamide: 1H-NMR (CDCl3) δ 8.48-8.43 (1H, m), 8.10-7.76 (3H, m), 7.48-7.20 (8H, m), 6.61 (1H, br.s), 3.43-3.24 (2H, m), 2.73-2.59 (2H, m), 2.37 (3H, s), 2.25 (3H, s).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-4d436dcfa0b545c9936f974eda569517
来源数据集: uspto-grants-2006_02
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07001917B2
来源说明: uspto-grants-2006_02

反应 SMILES

[CH3:1][C:2]1[C:6]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)=[C:5]([CH3:13])[N:4]([C:14]2[N:19]=[CH:18][C:17]([CH2:20][CH2:21][NH:22][C:23](=[O:31])OC3C=CC=CC=3)=[CH:16][CH:15]=2)[N:3]=1.[C:32]1([S:42]([NH2:45])(=[O:44])=[O:43])[CH:37]=[CH:36][CH:35]=[C:34]([S:38]([NH2:41])(=[O:40])=[O:39])[CH:33]=1>>[CH3:1][C:2]1[C:6]([C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=2)=[C:5]([CH3:13])[N:4]([C:14]2[N:19]=[CH:18][C:17]([CH2:20][CH2:21][NH:22][C:23]([NH:45][S:42]([C:32]3[CH:37]=[CH:36][CH:35]=[C:34]([S:38]([NH2:41])(=[O:40])=[O:39])[CH:33]=3)(=[O:44])=[O:43])=[O:31])=[CH:16][CH:15]=2)[N:3]=1