HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Formylbenzoic acid → 1,3-Bis(cyclohexylmethyl)-5,6-diaminouracil
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Formylbenzoic acid | HCID 12088 | — |
| Reactant | 6-Amino 1,3-bis(cyclohexylmethyl)-5-nitrosouracil | HCID 22244970 | — |
| Reactant | HCID 178525288 | HCID 178525288 | — |
| Product | 1,3-Bis(cyclohexylmethyl)-5,6-diaminouracil | HCID 22244975 | — |
| Product | HCID 178524287 | HCID 178524287 | — |
Reaction Steps
1,3-Bis(cyclohexylmethyl)-5,6-diaminouracil was prepared as in part (d) of Example 1 by reduction of 1, 6-amino 1,3-bis(cyclohexylmethyl)-5-nitrosouracil (1.00 g) and immediately condensed with 4-formylbenzoic acid (Aldrich, 1.424 g) by the method of J. Perumattam (Synthetic Commun. 1989, 19: 3367–3370) to give title compound as an off-white solid an off-white solid (720 mg, 54%), m.p. >300° C.; 1H-NMR (DMSO-d6) consistent with structure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07002012B2 |
| Source dataset | uspto-grants-2006_02 |
| ORD ID | ord-c3061fe80d3e40fca22e72ad628b209a |
| Source note | uspto-grants-2006_02 |