HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phthalaldehydic acid → 1,3-Bis(cyclohexylmethyl)-5,6-diaminouracil
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phthalaldehydic acid | HCID 8406 | — |
| Reactant | 6-Amino 1,3-bis(cyclohexylmethyl)-5-nitrosouracil | HCID 22244970 | — |
| Reactant | HCID 178525288 | HCID 178525288 | — |
| Product | 1,3-Bis(cyclohexylmethyl)-5,6-diaminouracil | HCID 22244975 | — |
| Product | HCID 178524287 | HCID 178524287 | — |
Reaction Steps
1,3-Bis(cyclohexylmethyl)-5,6-diaminouracil was prepared as in part (d) of Example 1 by reduction of 1, 6-amino 1,3-bis(cyclohexylmethyl)-5-nitrosouracil (2.00 g) and immediately condensed with 2-formylbenzoic acid (Aldrich, 1.424 g) by the method of J. Perumattam (Synthetic Commun. 1989, 19: 3367–3370) to give title compound as an off-white solid off-white solid (1.22 g, 46%), m.p. 271–274° C.; 1H-NMR (DMSO-d6) consistent with structure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07002012B2 |
| Source dataset | uspto-grants-2006_02 |
| ORD ID | ord-0ab4837efb1147698b9f1d5f0857df3e |
| Source note | uspto-grants-2006_02 |