HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aluminum bromide → 4-(4-fluorophenoxy)-5-[4-(methylsulfonyl)phenyl]-3(2H)-pyridazinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aluminum bromide | HCID 24409 | — |
| Reactant | 2-Benzyl-4-(4-fluorophenoxy)-5-[4-(methylsulfonyl)phenyl]-3(2H)-pyridazinone | HCID 9846581 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 4-(4-fluorophenoxy)-5-[4-(methylsulfonyl)phenyl]-3(2H)-pyridazinone | HCID 21934162 | — |
Reaction Steps
The title compound was prepared by treating 2-benzyl-4-(4-fluorophenoxy)-5-[4-(methylsulfonyl)phenyl]-3(2H)-pyridazinone (Example 75) with AlBr3 in toluene according to the procedure in Example 11 (yield: 1.8 g, 95%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07001895B2 |
| Source dataset | uspto-grants-2006_02 |
| ORD ID | ord-e87118ab7853444f87dda44a2479da3a |
| Source note | uspto-grants-2006_02 |