5-Chloro-3-(2-methylimidazol-1-ylmethyl)-pyridazine → HCID 22240171, compound

HRID 891878Notes

Reaction equation

HRID 891878 reaction equation
[F:1][CH:2]([F:19])[C:3]1[CH:4]=[C:5](B2OC(C)(C)C(C)(C)O2)[CH:6]=[CH:7][C:8]=1[F:9].[Cl:20][C:21]1[CH:22]=[C:23]([CH2:27][N:28]2[CH:32]=[CH:31][N:30]=[C:29]2[CH3:33])[N:24]=[N:25][CH:26]=1>>[ClH:20].[F:19][CH:2]([F:1])[C:3]1[CH:4]=[C:5]([C:21]2[CH:22]=[C:23]([CH2:27][N:28]3[CH:32]=[CH:31][N:30]=[C:29]3[CH3:33])[N:24]=[N:25][CH:26]=2)[CH:6]=[CH:7][C:8]=1[F:9]

Participants

3

Reactant 2

HCID 117890255-Chloro-3-(2-methylimidazol-1-ylmethyl)-pyridazineHCID 22240278HCID 22240278, compound

Product 1

HCID 22240171HCID 22240171, compound

Procedure

The title compound, MS: m/e=319.4 (M+H+), was prepared from 2-(3-difluoromethyl-4-fluoro-phenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane and 5-chloro-3-(2-methyl-imidazol-1-yl-methyl)-pyridazine.

Sources & evidence

ORD record
ord-48f8bd0592684095a657c85af9774b7b
Source dataset
uspto-grants-2006_02
Patent number
US07005432B2

Reaction notes

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