(4-Fluoro-3-methylphenyl)boronic acid → HCID 22240221, compound

HRID 891887Notes

Reaction equation

HRID 891887 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5](B(O)O)=[CH:4][C:3]=1[CH3:11].[Cl:12][C:13]1[CH:14]=[C:15]([CH2:19][N:20]2[CH:24]=[CH:23][N:22]=[C:21]2[CH3:25])[N:16]=[N:17][CH:18]=1>>[ClH:12].[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:13]2[CH:14]=[C:15]([CH2:19][N:20]3[CH:24]=[CH:23][N:22]=[C:21]3[CH3:25])[N:16]=[N:17][CH:18]=2)=[CH:4][C:3]=1[CH3:11]

Participants

3

Reactant 2

HCID 2774580(4-Fluoro-3-methylphenyl)boronic acidHCID 117890255-Chloro-3-(2-methylimidazol-1-ylmethyl)-pyridazine

Product 1

HCID 22240221HCID 22240221, compound

Procedure

The title compound, MS: m/e=283.1 (M+H+), was prepared from 4-fluoro-3-methylphenylboronic acid (commercially available) and 5-chloro-3-(2-methyl-imidazol-1-yl-methyl)-pyridazine.

Sources & evidence

ORD record
ord-e1cb3b3baab042eca44f8d55c715af73
Source dataset
uspto-grants-2006_02
Patent number
US07005432B2

Reaction notes

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