(3-Chlorophenyl)boronic acid → 5-(3-Chloro-phenyl)-3-(2-methyl-imidazol-1-yl-methyl)-pyridazine Hydrochloride

HRID 891891Notes

Reaction equation

HRID 891891 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4](B(O)O)[CH:5]=[CH:6][CH:7]=1.Cl[C:12]1[CH:13]=[C:14]([CH2:18][N:19]2[CH:23]=[CH:22][N:21]=[C:20]2[CH3:24])[N:15]=[N:16][CH:17]=1>>[ClH:1].[Cl:1][C:2]1[CH:3]=[C:4]([C:12]2[CH:13]=[C:14]([CH2:18][N:19]3[CH:23]=[CH:22][N:21]=[C:20]3[CH3:24])[N:15]=[N:16][CH:17]=2)[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 2734323(3-Chlorophenyl)boronic acidHCID 117890255-Chloro-3-(2-methylimidazol-1-ylmethyl)-pyridazine

Product 1

HCID 222402975-(3-Chloro-phenyl)-3-(2-methyl-imidazol-1-yl-methyl)-pyridazine Hydrochloride

Procedure

The title compound, MS: m/e=285.2 (M+H+), was prepared from 3-chlorophenylboronic acid and 5-chloro-3-(2-methyl-imidazol-1-yl-methyl)-pyridazine.

Sources & evidence

ORD record
ord-d5d07f93e6184ab5888ed9c90a710674
Source dataset
uspto-grants-2006_02
Patent number
US07005432B2

Reaction notes

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