5-Chloro-3-(2-methylimidazol-1-ylmethyl)-pyridazine → HCID 22240168, compound

HRID 891897Notes

Reaction equation

HRID 891897 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5](B2OC(C)(C)C(C)(C)O2)=[CH:4][C:3]=1[CH:17]([F:19])[F:18].Cl[C:21]1[CH:22]=[C:23]([CH2:27][N:28]2[CH:32]=[CH:31][N:30]=[C:29]2[CH3:33])[N:24]=[N:25][CH:26]=1>>[ClH:1].[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:21]2[CH:22]=[C:23]([CH2:27][N:28]3[CH:32]=[CH:31][N:30]=[C:29]3[CH3:33])[N:24]=[N:25][CH:26]=2)=[CH:4][C:3]=1[CH:17]([F:18])[F:19]

Participants

3

Reactant 2

HCID 117890255-Chloro-3-(2-methylimidazol-1-ylmethyl)-pyridazineHCID 222401272-[4-Chloro-3-(difluoromethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Product 1

HCID 22240168HCID 22240168, compound

Procedure

The title compound, MS: m/e=335.3 (M+H+), was prepared from 2-(4-chloro-3-difluoromethyl-phenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane and 5-chloro-3-(2-methyl-imidazol-1-yl-methyl)-pyridazine.

Sources & evidence

ORD record
ord-39cfecf5e29744d2967fd3d76ebfef03
Source dataset
uspto-grants-2006_02
Patent number
US07005432B2

Reaction notes

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