5-Chloro-3-(2-methylimidazol-1-ylmethyl)-pyridazine → HCID 22240283, compound

HRID 891899Notes

Reaction equation

HRID 891899 reaction equation
[F:1][CH:2]([F:22])[C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[CH:9]=[C:8](B1OC(C)(C)C(C)(C)O1)[CH:7]=[CH:6]2.[Cl:23][C:24]1[CH:25]=[C:26]([CH2:30][N:31]2[CH:35]=[CH:34][N:33]=[C:32]2[CH3:36])[N:27]=[N:28][CH:29]=1>>[ClH:23].[F:22][CH:2]([F:1])[C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[CH:9]=[C:8]([C:24]1[CH:25]=[C:26]([CH2:30][N:31]3[CH:35]=[CH:34][N:33]=[C:32]3[CH3:36])[N:27]=[N:28][CH:29]=1)[CH:7]=[CH:6]2

Participants

3

Reactant 2

HCID 117890255-Chloro-3-(2-methylimidazol-1-ylmethyl)-pyridazineHCID 22240162HCID 22240162, compound

Product 1

HCID 22240283HCID 22240283, compound

Procedure

The title compound, MS: m/e 351.4 (M+H+), was prepared from 2-(6-difluoromethyl-naphthalen-2-yl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane and 5-chloro-3-(2-methyl-imidazol-1-yl-methyl)-pyridazine.

Sources & evidence

ORD record
ord-c61640b923fb4f3fbf30ff33421d9fa4
Source dataset
uspto-grants-2006_02
Patent number
US07005432B2

Reaction notes

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