3-(Trifluoromethoxy)phenylboronic Acid (contains varying amounts of Anhydride) → HCID 22240274, compound

HRID 891900Notes

Reaction equation

HRID 891900 reaction equation
[F:1][C:2]([F:14])([F:13])[O:3][C:4]1[CH:5]=[C:6](B(O)O)[CH:7]=[CH:8][CH:9]=1.[Cl:15][C:16]1[CH:17]=[C:18]([CH2:22][N:23]2[CH:27]=[CH:26][N:25]=[C:24]2[CH3:28])[N:19]=[N:20][CH:21]=1>>[ClH:15].[CH3:28][C:24]1[N:23]([CH2:22][C:18]2[N:19]=[N:20][CH:21]=[C:16]([C:6]3[CH:7]=[CH:8][CH:9]=[C:4]([O:3][C:2]([F:14])([F:13])[F:1])[CH:5]=3)[CH:17]=2)[CH:27]=[CH:26][N:25]=1

Participants

3

Reactant 2

HCID 27343853-(Trifluoromethoxy)phenylboronic Acid (contains varying amounts of Anhydride)HCID 117890255-Chloro-3-(2-methylimidazol-1-ylmethyl)-pyridazine

Product 1

HCID 22240274HCID 22240274, compound

Procedure

The title compound, MS: m/e=335.3 (M+H+), was prepared from 3-(trifluoromethoxy)phenylboronic acid and 5-chloro-3-(2-methyl-imidazol-1-yl-methyl)-pyridazine.

Sources & evidence

ORD record
ord-111ddbf9b61947098571460ec2b02393
Source dataset
uspto-grants-2006_02
Patent number
US07005432B2

Reaction notes

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