5-Chloro-3-(2-methylimidazol-1-ylmethyl)-pyridazine → HCID 22240188, compound

HRID 891907Notes

Reaction equation

HRID 891907 reaction equation
[CH3:1][O:2][C:3]1[CH:12]=[CH:11][CH:10]=[C:9]2[C:4]=1[CH:5]=[CH:6][CH:7]=[C:8]2B1OC(C)(C)C(C)(C)O1.[Cl:22][C:23]1[CH:24]=[C:25]([CH2:29][N:30]2[CH:34]=[CH:33][N:32]=[C:31]2[CH3:35])[N:26]=[N:27][CH:28]=1>>[ClH:22].[CH3:1][O:2][C:3]1[CH:12]=[CH:11][CH:10]=[C:9]2[C:4]=1[CH:5]=[CH:6][CH:7]=[C:8]2[C:23]1[CH:24]=[C:25]([CH2:29][N:30]2[CH:34]=[CH:33][N:32]=[C:31]2[CH3:35])[N:26]=[N:27][CH:28]=1

Participants

3

Reactant 2

HCID 117890255-Chloro-3-(2-methylimidazol-1-ylmethyl)-pyridazineHCID 22240248HCID 22240248, compound

Product 1

HCID 22240188HCID 22240188, compound

Procedure

The title compound, MS: m/e=331.4 (M+H+), was prepared from 2-(5-methoxy-naphthalen-1-yl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane and 5-chloro-3-(2-methyl-imidazol-1-yl-methyl)-pyridazine.

Sources & evidence

ORD record
ord-f89418350ea047638edbac7beecd603a
Source dataset
uspto-grants-2006_02
Patent number
US07005432B2

Reaction notes

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