5-Chloro-3-(2-methylimidazol-1-ylmethyl)-pyridazine → HCID 22240313, compound

HRID 891909Notes

Reaction equation

HRID 891909 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5](B2OC(C)(C)C(C)(C)O2)[CH:6]=[C:7]([C:9]([F:12])([F:11])[F:10])[CH:8]=1.[Cl:22][C:23]1[CH:24]=[C:25]([CH2:29][N:30]2[CH:34]=[CH:33][N:32]=[C:31]2[CH3:35])[N:26]=[N:27][CH:28]=1>>[ClH:22].[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:23]2[CH:24]=[C:25]([CH2:29][N:30]3[CH:34]=[CH:33][N:32]=[C:31]3[CH3:35])[N:26]=[N:27][CH:28]=2)[CH:6]=[C:7]([C:9]([F:10])([F:11])[F:12])[CH:8]=1

Participants

3

Reactant 2

HCID 117890255-Chloro-3-(2-methylimidazol-1-ylmethyl)-pyridazineHCID 222403032-(3-Methoxy-5-trifluoromethyl-phenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane

Product 1

HCID 22240313HCID 22240313, compound

Procedure

The title compound, MS: m/e=349.4 (M+H+), was prepared from 2-(3-methoxy-5-trifluoromethyl-phenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane and 5-chloro-3-(2-methyl-imidazol-1-yl-methyl)-pyridazine.

Sources & evidence

ORD record
ord-d68dc6fd36bb44668ec2152a93cbb4cf
Source dataset
uspto-grants-2006_02
Patent number
US07005432B2

Reaction notes

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