5-Chloro-3-(2-methylimidazol-1-ylmethyl)-pyridazine → HCID 22240159, compound

HRID 891912Notes

Reaction equation

HRID 891912 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5](B2OC(C)(C)C(C)(C)O2)=[CH:4][C:3]=1[O:17][CH3:18].Cl[C:20]1[CH:21]=[C:22]([CH2:26][N:27]2[CH:31]=[CH:30][N:29]=[C:28]2[CH3:32])[N:23]=[N:24][CH:25]=1>>[ClH:1].[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:20]2[CH:21]=[C:22]([CH2:26][N:27]3[CH:31]=[CH:30][N:29]=[C:28]3[CH3:32])[N:23]=[N:24][CH:25]=2)=[CH:4][C:3]=1[O:17][CH3:18]

Participants

3

Reactant 2

HCID 117890255-Chloro-3-(2-methylimidazol-1-ylmethyl)-pyridazineHCID 222402822-(4-Chloro-3-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Product 1

HCID 22240159HCID 22240159, compound

Procedure

The title compound, MS: m/e=315.3 (M+H+), was prepared from 2-(4-chloro-3-methoxy-phenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane and 5-chloro-3-(2-methyl-imidazol-1-yl-methyl)-pyridazine.

Sources & evidence

ORD record
ord-c23be11e81984693970e08d92700bcfc
Source dataset
uspto-grants-2006_02
Patent number
US07005432B2

Reaction notes

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