5-Chloro-3-(2-methylimidazol-1-ylmethyl)-pyridazine → HCID 22240180, compound

HRID 891918Notes

Reaction equation

HRID 891918 reaction equation
[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH:7]=[CH:8][C:9](B3OC(C)(C)C(C)(C)O3)=[CH:10]2)=[CH:5][CH:4]=1.[Cl:22][C:23]1[CH:24]=[C:25]([CH2:29][N:30]2[CH:34]=[CH:33][N:32]=[C:31]2[CH3:35])[N:26]=[N:27][CH:28]=1>>[ClH:22].[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH:7]=[CH:8][C:9]([C:23]3[CH:24]=[C:25]([CH2:29][N:30]4[CH:34]=[CH:33][N:32]=[C:31]4[CH3:35])[N:26]=[N:27][CH:28]=3)=[CH:10]2)=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 117890255-Chloro-3-(2-methylimidazol-1-ylmethyl)-pyridazineHCID 22240190HCID 22240190, compound

Product 1

HCID 22240180HCID 22240180, compound

Procedure

The title compound, MS: m/e 331.3 (M+H+), was prepared from 2-(7-methoxy-naphthalen-2-yl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane and 5-chloro-3-(2-methyl-imidazol-1-yl-methyl)-pyridazine.

Sources & evidence

ORD record
ord-b0e7d35eaa6148d38d9360e083606f61
Source dataset
uspto-grants-2006_02
Patent number
US07005432B2

Reaction notes

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