5-Chloro-3-(2-methylimidazol-1-ylmethyl)-pyridazine → HCID 22240292, compound

HRID 891920Notes

Reaction equation

HRID 891920 reaction equation
[F:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5](B2OC(C)(C)C(C)(C)O2)=[CH:4][CH:3]=1.[Cl:21][C:22]1[CH:23]=[C:24]([CH2:28][N:29]2[CH:33]=[CH:32][N:31]=[C:30]2[CH3:34])[N:25]=[N:26][CH:27]=1>>[ClH:21].[F:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]([C:22]2[CH:23]=[C:24]([CH2:28][N:29]3[CH:33]=[CH:32][N:31]=[C:30]3[CH3:34])[N:25]=[N:26][CH:27]=2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 117890255-Chloro-3-(2-methylimidazol-1-ylmethyl)-pyridazineHCID 222401162-(4-Fluoronaphthalen-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Product 1

HCID 22240292HCID 22240292, compound

Procedure

The title compound, MS: m/e=319.3 (M+H+), was prepared from 2-(4-fluoro-naphthalen-1-yl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane and 5-chloro-3-(2-methyl-imidazol-1-yl-methyl)-pyridazine.

Sources & evidence

ORD record
ord-4e73b6e962a54662b639117fb5444c23
Source dataset
uspto-grants-2006_02
Patent number
US07005432B2

Reaction notes

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