HCID 22240124, compound → HCID 22240210, compound
Reaction equation
[F:1][CH:2]([F:19])[C:3]1[CH:4]=[C:5](B2OC(C)(C)C(C)(C)O2)[CH:6]=[CH:7][C:8]=1[F:9].[Cl:20][C:21]1[C:22]([CH3:32])=[C:23]([N:27]2[CH:31]=[CH:30][N:29]=[CH:28]2)[N:24]=[N:25][CH:26]=1>>[ClH:20].[F:19][CH:2]([F:1])[C:3]1[CH:4]=[C:5]([C:21]2[C:22]([CH3:32])=[C:23]([N:27]3[CH:31]=[CH:30][N:29]=[CH:28]3)[N:24]=[N:25][CH:26]=2)[CH:6]=[CH:7][C:8]=1[F:9]Participants
3
Procedure
The title compound, MS: m/e=305.2 (M+H+), was prepared from 2-(3-difluoromethyl-4-fluoro-phenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane and 5-chloro-3-imidazol-1-yl-methyl-pyridazine.
Sources & evidence
- ORD record
- ord-cc336fe75aa547db87e23aa2987699dc
- Source dataset
- uspto-grants-2006_02
- Patent number
- US07005432B2
Reaction notes
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