5-Chloro-3-(2-methylimidazol-1-ylmethyl)-pyridazine → HCID 22240153, compound
Reaction equation
[CH3:1][O:2][C:3]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[CH:6]=[CH:5][C:4]=1B1OC(C)(C)C(C)(C)O1.Cl[C:23]1[CH:24]=[C:25]([CH2:29][N:30]2[CH:34]=[CH:33][N:32]=[C:31]2[CH3:35])[N:26]=[N:27][CH:28]=1>>[CH3:1][O:2][C:3]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[CH:6]=[CH:5][C:4]=1[C:23]1[CH:24]=[C:25]([CH2:29][N:30]2[CH:34]=[CH:33][N:32]=[C:31]2[CH3:35])[N:26]=[N:27][CH:28]=1Participants
3
Procedure
The title compound, MS: m/e=331.4 (M+H+), was prepared from 2-(1-methoxy-naphthalen-2-yl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane and 5-chloro-3-(2-methyl-imidazol-1-yl-methyl)-pyridazine.
Sources & evidence
- ORD record
- ord-3b84ef8b658141efb0128b7f99401671
- Source dataset
- uspto-grants-2006_02
- Patent number
- US07005432B2
Reaction notes
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