5-Chloro-3-(2-methylimidazol-1-ylmethyl)-pyridazine → HCID 22240142, compound

HRID 891929Notes

Reaction equation

HRID 891929 reaction equation
CC1(C)C(C)(C)OB([C:9]2[C:18]3[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=3)[C:12]([CH3:19])=[CH:11][CH:10]=2)O1.[Cl:21][C:22]1[CH:23]=[C:24]([CH2:28][N:29]2[CH:33]=[CH:32][N:31]=[C:30]2[CH3:34])[N:25]=[N:26][CH:27]=1>>[ClH:21].[CH3:34][C:30]1[N:29]([CH2:28][C:24]2[N:25]=[N:26][CH:27]=[C:22]([C:9]3[C:18]4[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=4)[C:12]([CH3:19])=[CH:11][CH:10]=3)[CH:23]=2)[CH:33]=[CH:32][N:31]=1

Participants

3

Reactant 2

HCID 117890255-Chloro-3-(2-methylimidazol-1-ylmethyl)-pyridazineHCID 222401124,4,5,5-Tetramethyl-2-(4-methylnaphthalen-1-yl)-1,3,2-dioxaborolane

Product 1

HCID 22240142HCID 22240142, compound

Procedure

The title compound, MS: m/e=351.9 (M+H+), was prepared from 4,4,5,5-tetramethyl-2-(4-methyl-naphthalen-1-yl)-[1,3,2]dioxaborolane and 5-chloro-3-(2-methyl-imidazol-1-ylmethyl)-pyridazine.

Sources & evidence

ORD record
ord-07a1cdaf52a24e72adcca29e612d463c
Source dataset
uspto-grants-2006_02
Patent number
US07005432B2

Reaction notes

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