5-Chloro-3-(2-methylimidazol-1-ylmethyl)-pyridazine → HCID 22240302, compound

HRID 891934Notes

Reaction equation

HRID 891934 reaction equation
[F:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][C:6](B(O)O)=[CH:7]2.Cl[C:16]1[CH:17]=[C:18]([CH2:22][N:23]2[CH:27]=[CH:26][N:25]=[C:24]2[CH3:28])[N:19]=[N:20][CH:21]=1>>[F:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][C:6]([C:16]1[CH:17]=[C:18]([CH2:22][N:23]3[CH:27]=[CH:26][N:25]=[C:24]3[CH3:28])[N:19]=[N:20][CH:21]=1)=[CH:7]2

Participants

3

Reactant 2

HCID 117890255-Chloro-3-(2-methylimidazol-1-ylmethyl)-pyridazineHCID 22240281HCID 22240281, compound

Product 1

HCID 22240302HCID 22240302, compound

Procedure

The title compound, MS: m/e=319.4 (M+H+), was prepared from 5-fluoro-naphthalene-2-boronic acid and 5-chloro-3-(2-methyl-imidazol-1-yl-methyl)-pyridazine.

Sources & evidence

ORD record
ord-330ccb83d17046e989347c07fef3e532
Source dataset
uspto-grants-2006_02
Patent number
US07005432B2

Reaction notes

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