5-Chloro-3-(2-methylimidazol-1-ylmethyl)-pyridazine → HCID 22240266, compound
Reaction equation
[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH2:7][CH2:8][C:9](B(O)O)=[CH:10]2)=[CH:5][CH:4]=1.[Cl:16][C:17]1[CH:18]=[C:19]([CH2:23][N:24]2[CH:28]=[CH:27][N:26]=[C:25]2[CH3:29])[N:20]=[N:21][CH:22]=1>>[ClH:16].[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH2:7][CH2:8][C:9]([C:17]3[CH:18]=[C:19]([CH2:23][N:24]4[CH:28]=[CH:27][N:26]=[C:25]4[CH3:29])[N:20]=[N:21][CH:22]=3)=[CH:10]2)=[CH:5][CH:4]=1Participants
3
Procedure
The title compound, MS: m/e=333.3 (M+H+), was prepared from 7-methoxy-3,4-dihydro-naphthalene-2-boronic acid and 5-chloro-3-(2-methyl-imidazol-1-yl-methyl)-pyridazine.
Sources & evidence
- ORD record
- ord-a55bcd8056d346609b1eb0e4b1320a12
- Source dataset
- uspto-grants-2006_02
- Patent number
- US07005432B2
Reaction notes
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