5-Chloro-3-(2-methylimidazol-1-ylmethyl)-pyridazine → HCID 22240205, compound
Reaction equation
[CH3:1][C:2]1[CH:11]=[C:10]([CH3:12])[CH:9]=[C:8]2[C:3]=1[CH2:4][CH2:5][C:6](B(O)O)=[CH:7]2.[Cl:16][C:17]1[CH:18]=[C:19]([CH2:23][N:24]2[CH:28]=[CH:27][N:26]=[C:25]2[CH3:29])[N:20]=[N:21][CH:22]=1>>[ClH:16].[CH3:1][C:2]1[CH:11]=[C:10]([CH3:12])[CH:9]=[C:8]2[C:3]=1[CH2:4][CH2:5][C:6]([C:17]1[CH:18]=[C:19]([CH2:23][N:24]3[CH:28]=[CH:27][N:26]=[C:25]3[CH3:29])[N:20]=[N:21][CH:22]=1)=[CH:7]2Participants
3
Procedure
The title compound, MS: m/e=331.3 (M+H+), was prepared from 5,7-dimethyl-3,4-dihydro-naphthalene-2-boronic acid and 5-chloro-3-(2-methyl-imidazol-1-yl-methyl)-pyridazine.
Sources & evidence
- ORD record
- ord-5058f5cbcab749a78c97d31425a07033
- Source dataset
- uspto-grants-2006_02
- Patent number
- US07005432B2
Reaction notes
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