5-Chloro-3-(2-methylimidazol-1-ylmethyl)-pyridazine → HCID 22240257, compound

HRID 891941Notes

Reaction equation

HRID 891941 reaction equation
[CH3:1][O:2][C:3]1[CH:12]=[CH:11][CH:10]=[C:9]2[C:4]=1[CH2:5][CH2:6][C:7](B(O)O)=[CH:8]2.[Cl:16][C:17]1[CH:18]=[C:19]([CH2:23][N:24]2[CH:28]=[CH:27][N:26]=[C:25]2[CH3:29])[N:20]=[N:21][CH:22]=1>>[ClH:16].[CH3:1][O:2][C:3]1[CH:12]=[CH:11][CH:10]=[C:9]2[C:4]=1[CH2:5][CH2:6][C:7]([C:17]1[CH:18]=[C:19]([CH2:23][N:24]3[CH:28]=[CH:27][N:26]=[C:25]3[CH3:29])[N:20]=[N:21][CH:22]=1)=[CH:8]2

Participants

3

Reactant 2

HCID 117890255-Chloro-3-(2-methylimidazol-1-ylmethyl)-pyridazineHCID 22176436HCID 22176436, compound

Product 1

HCID 22240257HCID 22240257, compound

Procedure

The title compound, MS: m/e=333.3 (M+H+), was prepared from 5-methoxy-3,4-dihydro-naphthalene-2-boronic acid and 5-chloro-3-(2-methyl-imidazol-1-yl-methyl)-pyridazine.

Sources & evidence

ORD record
ord-f2000d5217dc4febb64ecbc25b9409ca
Source dataset
uspto-grants-2006_02
Patent number
US07005432B2

Reaction notes

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