HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrrolidine → (4-Bromo-2-methyl-phenyl)-pyrrolidin-1-yl-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 4-Bromo-2-methylbenzoic acid | HCID 99570 | — |
| Reactant | Tributylthiourea | HCID 3032425 | — |
| Solvent | Oxolane--water (1/1) | HCID 21881883 | — |
| Product | (4-Bromo-2-methyl-phenyl)-pyrrolidin-1-yl-methanone | HCID 11818009 | — |
Reaction Steps
Prepared analogously to Example 2a from 4-bromo-2-methylbenzoic acid, pyrrolidine, tBtU and N-ethyl-diisopropylamine in tetrahydrofuran/water 9:1
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07005437B2 |
| Source dataset | uspto-grants-2006_02 |
| ORD ID | ord-e9fb826f81da42ebaf583b3bb13667b9 |
| Source note | uspto-grants-2006_02 |