2-Chloroquinoline → 3-[(N-Methyl-N-quinolin-2-yl-amino)-methyl]-phenol

HRID 892141Notes

Reaction equation

HRID 892141 reaction equation
[CH3:1][NH:2][CH2:3][C:4]1[CH:5]=[C:6]([O:10]COCCOC)[CH:7]=[CH:8][CH:9]=1.Cl[C:18]1[CH:27]=[CH:26][C:25]2[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=2)[N:19]=1>>[CH3:1][N:2]([CH2:3][C:4]1[CH:5]=[C:6]([OH:10])[CH:7]=[CH:8][CH:9]=1)[C:18]1[CH:27]=[CH:26][C:25]2[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=2)[N:19]=1

Participants

3

Reactant 2

HCID 119282-ChloroquinolineHCID 22241370HCID 22241370, compound

Product 1

HCID 222413493-[(N-Methyl-N-quinolin-2-yl-amino)-methyl]-phenol

Procedure

MS (ESI) 265 (M+H)+. Prepared from 3-[(methylamino)-methyl]-(2-methoxyethoxy-methoxy)benzene (example 28) and 2-chloro-quinoline.

Sources & evidence

ORD record
ord-f6d97b91c16645b8a1a00730b1421585
Source dataset
uspto-grants-2006_02
Patent number
US07005440B1

Reaction notes

Loading…