HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl Peroxide → HCID 22241465, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl Peroxide | HCID 7187 | — |
| Reactant | N-Bromosuccinamide | HCID 9834204 | — |
| Reactant | HCID 22241285 | HCID 22241285 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | HCID 22241465 | HCID 22241465 | — |
Reaction Steps
A solution of 2-methyl-6,8-difluoroquinoline (0.147 g, 0.820 mmoles, Example 26a), benzoyl peroxide (9.93 mg, 0.0410 mmoles), and N-bromosuccinamide (0.168 g, 0.943 mmoles) in carbon tetrachloride (20 mL) is heated to reflux for 18 hours. The reaction is concentrated and the resulting residue purified by column chromatography (silica, 3:1 CH2Cl2:hexane, then CH2Cl2) to yield the title compound as a white solid. MS (ESI) 258, 260 (M+H)+, Br pattern.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07005440B1 |
| Source dataset | uspto-grants-2006_02 |
| ORD ID | ord-05791a76b10f451ab52a8bfe6b1c4722 |
| Source note | uspto-grants-2006_02 |