3-Methyl-5-(quinolin-2-ylmethoxy)-phenol → Ethyl {2-methyl-6-[3-methyl-5-(quinolin-2-ylmethoxy)-phenoxymethyl]-phenoxy}-acetate
Reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([OH:20])[CH:5]=[C:6]([O:8][CH2:9][C:10]2[CH:19]=[CH:18][C:17]3[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=3)[N:11]=2)[CH:7]=1.Br[CH2:22][C:23]1[CH:35]=[CH:34][CH:33]=[C:32]([CH3:36])[C:24]=1[O:25][CH2:26][C:27]([O:29][CH2:30][CH3:31])=[O:28]>>[CH3:22][C:23]1[CH:35]=[CH:34][CH:33]=[C:32]([CH2:36][O:20][C:4]2[CH:5]=[C:6]([O:8][CH2:9][C:10]3[CH:19]=[CH:18][C:17]4[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=4)[N:11]=3)[CH:7]=[C:2]([CH3:1])[CH:3]=2)[C:24]=1[O:25][CH2:26][C:27]([O:29][CH2:30][CH3:31])=[O:28]Participants
3
Procedure
The title compound is prepared using essentially the same procedure used in example 35 except using 3-methyl-5-(quinolin-2-ylmethoxy)-phenol (example 55) in place of 3-(quinolin-2-ylmethoxy)-phenol and ethyl (2-bromomethyl-6-methyl-phenoxy)-acetate (example 43b) in place of (2-bromomethyl-6-methyl-phenoxy)-acetonitrile.
Sources & evidence
- ORD record
- ord-12e7f888403d4f1280d4760651791315
- Source dataset
- uspto-grants-2006_02
- Patent number
- US07005440B1
Reaction notes
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