関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Potassium Hydroxide | HCID 14797 | — |
| 反応物 | 2-chloro-N-(2-hydroxy-4-nitrophenyl)acetamide | HCID 19968389 | — |
| 溶媒 | Dimethyl Sulfoxide | HCID 679 | — |
| 生成物 | 7-nitro-3,4-dihydro-2H-1,4-benzoxazin-3-one | HCID 2763830 | 85% |
反応手順
A mixture of 8 (22 g) and powdered KOH (6.9 g) in DMSO (100 ml) was stirred at 95° C. for 30 min. and poured onto crushed ice (400 g). The resulting precipitate was collected and washed with H2O to give 9 (15.7 g, 85%): mp 230°-232° C.; MS m/e 194 (M+).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05118323 |
|---|
| 出典データセット | uspto-grants-1992_06 |
|---|
| ORD ID | ord-0b33cd03661144cdbccc1cf78e75bb00 |
|---|
| 出典メモ | uspto-grants-1992_06 |
|---|
