3-(Cycloundecen-1-yl)-1,2-diazacycloundec-2-ene → HCID 54736293, compound

HRID 892418Notes

Reaction equation

HRID 892418 reaction equation
[C:1]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[S:11][CH2:12][C:13]([O:15][CH2:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)=[O:14])(OC)=[O:2].C1(C2CCCCCCCCCC=2)CCCCCCCCNN=1>C1(C)C=CC=CC=1>[OH:2][C:1]1[C:5]2[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=2[S:11][C:12]=1[C:13]([O:15][CH2:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)=[O:14]

Participants

4

Reactant 2

HCID 536302743-(Cycloundecen-1-yl)-1,2-diazacycloundec-2-eneHCID 54285067HCID 54285067, compound

Product 1

HCID 54736293HCID 54736293, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

5 g (I5.8 mmol) of benzyl S-(2-carbomethoxyphenyl)-thioglycolate and 3 g (19.7 mmol) of diazabicycloundecene are heated under reflux in 100 ml of toluene. At the same time, about 50 ml of toluene are removed by distillation in the course of one hour. After cooling, the mixture is poured into 2 N HCl and extracted with CH2Cl2. The residue is purified by filtration through silica gel using toluene as the eluent.

Workup

  1. customAt the same time, about 50 ml of toluene are removed by distillation in the course of one hour
  2. temperatureAfter cooling
  3. additionthe mixture is poured into 2 N HCl
  4. extractionextracted with CH2Cl2
  5. filtrationThe residue is purified by filtration through silica gel

Sources & evidence

ORD record
ord-2efe70076790471d9c88f0797eab162f
Source dataset
uspto-grants-1992_06
Patent number
US05118680

Reaction notes

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