Water → HCID 178458309, compound

Participants

Reaction Steps

A solution of 2-propoxybenzamidine methanesulphonate (2.9g), 10% sodium hydroxide (4 ml) and ethyl 4-oxalacetate (1.6g) in water (8 ml) was stirred at ambient temperature for 42 hours. The reaction mixture was evaporated to dryness to yield a crude product which was washed with dilute hydrochloric acid and water to 5 yield the title compound, 0.82g, m.p. 179.5°-181.5° C. A sample (0.4g) was recrystallised from ethanol to yield the pure title compound, 0.24 g, m.p. 184°-5° C.

Provenance & Evidence