HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethyl Sulfide → 4,8,8-Trimethyl-1-oxaspiro[2.5]oct-4-ene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethyl Sulfide | HCID 1068 | — |
| Reactant | Dimethyl Sulfate | HCID 6497 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 2,6,6-Trimethyl-2-cyclohexen-1-one | HCID 88332 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | 4,8,8-Trimethyl-1-oxaspiro[2.5]oct-4-ene | HCID 11768771 | 73% |
Reaction Steps
Prepared under the conditions described in a., starting from 25.0 g (181 mmol) of 2,6,6-trimethyl-2-cyclohexen-1-one, 31.9 g (253 mmol) of (CH3)2SO4, 17.0 g (274 mmol) of (CH3)2S and 43.0 g (1086 mmol) of NaOH in 60 ml of DMSO. 22.09 G of the desired product, 91% pure, were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05118865 |
| Source dataset | uspto-grants-1992_06 |
| ORD ID | ord-6e174837e8974c6b9cde3b4b240f3875 |
| Source note | uspto-grants-1992_06 |