2-Mercaptoethanol → HCID 14988014, compound

HRID 892733Notes

Reaction equation

HRID 892733 reaction equation
[SH:1][CH2:2][CH2:3][OH:4].[CH3:5][C:6]1([CH3:9])[CH2:8][NH:7]1>C(COC)OC>[NH2:7][C:6]([CH3:9])([CH3:8])[CH2:5][S:1][CH2:2][CH2:3][OH:4]

Participants

4

Reactant 2

HCID 15672-MercaptoethanolHCID 2272442,2-Dimethylaziridine

Product 1

HCID 14988014HCID 14988014, compound

Reagents, catalysts & solvents 1

HCID 80711,2-DimethoxyethaneSolvent

Conditions

Temperature
70 °C

Procedure

234 g of 2-mercaptoethanol are dissolved in 90 ml of dimethoxyethane. 63.3 g of 2,2-dimethylaziridine are added dropwise to this solution and the mixture is stirred at 70° C. for 4 hours and concentrated, and the residue is distilled in a water jet vacuum. B.p.: 141°-142° C. (at 20 mbar); M.p.: 49°-51°;

Workup

  1. concentrationconcentrated
  2. distillationthe residue is distilled in a water jet vacuum

Sources & evidence

ORD record
ord-3907d43257fb44b79bf14e2b526fffee
Source dataset
uspto-grants-1992_06
Patent number
US05120732

Reaction notes

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