HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 892738Generated: October 31, 2026
Acetic Anhydride → 2-(Acetyloxy)butanoic acid
https://huagongshe.com/reaction/892738
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 2-Hydroxybutyric Acid | HCID 11266 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | 2-(Acetyloxy)butanoic acid | HCID 13327294 | 100% |
Reaction Steps
A mixture of 5.00 g (48.0 mmols) of 2-hydroxybutyric acid, 4.98 ml (52.8 mmols) of acetic anhydride and 60 ml of pyridine was stirred at 0° C. for 10 minutes. After concentration under reduced pressure, the residue was purified by silica gel column chromatography (eluent; chloroform) to give 7.01 g (yield, 100%) of 2-acetoxybutyric acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05120737 |
|---|
| Source dataset | uspto-grants-1992_06 |
|---|
| ORD ID | ord-cf7d07f448c94787b5da8d21f2b2b170 |
|---|
| Source note | uspto-grants-1992_06 |
|---|
