Magnesium Bromide → HCID 178419655, compound

HRID 892847Notes

Reaction equation

HRID 892847 reaction equation
[CH:1]1([Li])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][S:2]1.[Mg+2:12].[Br-:13].[Br-]>O(CC)CC>[CH:1]1([Mg:12][Br:13])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][S:2]1

Participants

4

Reactant 2

HCID 82241Magnesium BromideHCID 178506845HCID 178506845, compound

Product 1

HCID 178419655HCID 178419655, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

2-Thianaphthylmagnesium bromide is prepared from 2-thianaphthyllithium and MgBr2.OEt2. Using a procedure similar to that of Example 2, 3.85 g crude silylate product is isolated. Usual flash chromatography work-up results in an unidentified, insoluble purple solid. The desired product is isolated by adding 1M ethanolic HCl (95% of theoretical) to an ethereal solution of the free base. The product is a pale yellow solid (1.7 g, 72%); mp 235° C. (dec) (EtOH).

Workup

  1. customis isolated
  2. customUsual flash chromatography work-up results in an unidentified, insoluble purple solid

Sources & evidence

ORD record
ord-55506cddcfeb4cdab621127cbf2e4a59
Source dataset
uspto-grants-1992_06
Patent number
US05120764

Reaction notes

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