HCID 14994381, compound → HCID 11438468, compound

HRID 892869Notes

Reaction equation

HRID 892869 reaction equation
[NH2:1][C:2]1[C:7]([CH2:8][OH:9])=[C:6]([C:10]2[CH:15]=[CH:14][C:13]([F:16])=[CH:12][CH:11]=2)[C:5]([C:17]([O:19][CH3:20])=[O:18])=[C:4]([CH:21]([CH3:23])[CH3:22])[N:3]=1.[Cr](Cl)([O-])(=O)=O.[NH+]1C=CC=CC=1>ClCCl>[NH2:1][C:2]1[C:7]([CH:8]=[O:9])=[C:6]([C:10]2[CH:11]=[CH:12][C:13]([F:16])=[CH:14][CH:15]=2)[C:5]([C:17]([O:19][CH3:20])=[O:18])=[C:4]([CH:21]([CH3:23])[CH3:22])[N:3]=1

Participants

4

Reactant 2

HCID 14994381HCID 14994381, compoundHCID 178418287HCID 178418287, compound

Product 1

HCID 11438468HCID 11438468, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

20.7 g (65 mmol) of the compound from Example IV are dissolved in 1.5 1 of dichloromethane, 13.3 g (0.13 mol) of neutral alumina and 28 g (0.13 mol) of pyridinium chlorochromate are added and the mixture is stirred at room temperature for 1 hour.

Workup

  1. additionare added

Sources & evidence

ORD record
ord-415e5252c26b4c68b0371ef24e3d93cd
Source dataset
uspto-grants-1992_06
Patent number
US05120782

Reaction notes

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