反应详情

23.9 g (84 mmol) of the compound from Example VII are suspended in 1.6 1 of dichloromethane, 17.1 g of neutral alumina and 36.1 g (168 mmol) of pyridinium chlorochromate are added and the mixture is stirred at room temperature for 1 h. The suspension is filtered through 1.2 kg of silica gel (230-400 mesh) in a glass suction filter and washed without sucking dry using petroleum ether/ethyl acetate 3:2. The eluate is concentrated to dryness in vacuo and the residue which remains is stirred thoroughly in ether.

1. additionare added
2. filtrationThe suspension is filtered through 1.2 kg of silica gel (230-400 mesh) in a glass suction
3. filtrationfilter
4. washwashed
5. customwithout sucking dry
6. concentrationThe eluate is concentrated to dryness in vacuo
7. stirringthe residue which remains is stirred thoroughly in ether