Oleoylethanolamide → 2-(N-Oleoylamino)ethyl 3-[N-(2,2,5,5-tetramethyl-1,3-dioxane-4-carbonyl)amino]propionate

HRID 892905Notes

Reaction equation

HRID 892905 reaction equation
[OH:1][CH2:2][CH2:3][NH:4][C:5](=[O:23])[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12]/[CH:13]=[CH:14]\[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22].[CH3:24][C:25]1([CH3:41])[O:30][CH:29]([C:31]([NH:33][CH2:34][CH2:35][C:36](O)=[O:37])=[O:32])[C:28]([CH3:40])([CH3:39])[CH2:27][O:26]1>>[CH3:24][C:25]1([CH3:41])[O:30][CH:29]([C:31]([NH:33][CH2:34][CH2:35][C:36]([O:1][CH2:2][CH2:3][NH:4][C:5](=[O:23])[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12]/[CH:13]=[CH:14]\[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])=[O:37])=[O:32])[C:28]([CH3:40])([CH3:39])[CH2:27][O:26]1

Participants

3

Reactant 2

HCID 5283454OleoylethanolamideHCID 189385173-[N-(2,2,5,5-Tetramethyl-1,3-dioxane-4-carbonyl)amino]propionic acid

Product 1

HCID 677954162-(N-Oleoylamino)ethyl 3-[N-(2,2,5,5-tetramethyl-1,3-dioxane-4-carbonyl)amino]propionateYield 90%

Procedure

N-(2-Hydroxyethyl)oleamide (0.97 g) and 0.78 g of 3-[N-(2,2,5,5-tetramethyl-1,3-dioxane-4-carbonyl)amino]propionic acid were reacted in the same manner as in Example 15 to obtain 1.50 g of the title compound (yield: 90%).

Sources & evidence

ORD record
ord-7e3d4df7298d454894402ab00a268964
Source dataset
uspto-grants-1992_06
Patent number
US05120738

Reaction notes

Loading…