Benzoyl chloride → HCID 67916382, compound

HRID 892906Notes

Reaction equation

[OH:1][CH:2]([C:34]([CH3:38])([CH3:37])[CH2:35][OH:36])[C:3]([NH:5][CH2:6][CH2:7][C:8]([O:10][CH2:11][CH2:12][CH2:13][NH:14][C:15](=[O:33])[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22]/[CH:23]=[CH:24]\[CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32])=[O:9])=O.[C:39](Cl)(=[O:46])[C:40]1[CH:45]=[CH:44][CH:43]=[CH:42][CH:41]=1>>[CH2:39]([O:1][CH:2]([C:34]([CH3:38])([CH3:37])[C:35]([O:46][CH2:39][C:40]1[CH:45]=[CH:44][CH:43]=[CH:42][CH:41]=1)=[O:36])[CH2:3][NH:5][CH2:6][CH2:7][C:8]([O:10][CH2:11][CH2:12][CH2:13][NH:14][C:15](=[O:33])[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22]/[CH:23]=[CH:24]\[CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32])=[O:9])[C:40]1[CH:45]=[CH:44][CH:43]=[CH:42][CH:41]=1

Participants

Reactant 2

HCID 7412Benzoyl chloride

HCID 86745903HCID 86745903, compound

Product 1

HCID 67916382HCID 67916382, compoundYield 72.2%

Procedure

3-(N-Oleoylamino)propyl 3-[N-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)amino]propionate (270 mg) and 281 mg of benzoyl chloride were reacted in the same manner as in Example 36 to obtain 260 mg of the title compound (yield: 69%).

Sources & evidence

ORD record: ord-b01692ab33fd4f39bf83be19845b6839
Source dataset: uspto-grants-1992_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05120738

Reaction notes

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