Dichloromethane → HCID 10329663, compound

HRID 893007Notes

Reaction equation

HRID 893007 reaction equation
[OH:1][CH2:2][CH2:3][CH2:4][CH2:5][C:6]1[CH2:11][CH2:10][CH2:9][C:8](=[O:12])[CH:7]=1.C(Cl)Cl>CCOCC>[O:12]=[C:8]1[CH2:9][CH2:10][CH2:11][C:6]([CH2:5][CH2:4][CH2:3][CH:2]=[O:1])=[CH:7]1

Participants

4

Reactant 2

HCID 6344DichloromethaneHCID 10442085HCID 10442085, compound

Product 1

HCID 10329663HCID 10329663, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

Following the procedure of Corey, Tetrahedron Lett 2647 (1975), a mixture of 3-(4-hydroxybutyl)-cyclohex-2-en-1-one (539 mg) pyridinium dichromate (2.05 g) and methylene chloride (8.0 ml) is stirred for 25 hr at 20°-25°. The reaction is diluted with ether, filtered, dried over magnesium sulfate and concentrated to give the title compound, IR (neat) 2950, 1724, 1666, 1255, 1193, 888 cm-1.

Workup

  1. filtrationfiltered
  2. dry with materialdried over magnesium sulfate
  3. concentrationconcentrated

Sources & evidence

ORD record
ord-c043cdf4440e49c1b98ebebea94fda7a
Source dataset
uspto-grants-1992_06
Patent number
US05120843

Reaction notes

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