反应详情

2,4-dimethoxybenzonitrile (2 g) was mixed with pyridinium chloride (5.67 g) and the reaction mixture was fused at 210° C. for 2 hours. After being left to stand at room temperature overnight, the mixture was diluted with water and extracted into diethyl ether. The ether extracts were washed with water, dried over magnesium sulphate and concentrated to give a pink solid which was washed with petrol and air dried to give 2,4-dihydroxybenzonitrile (1.17 g) (m pt 176°-178° C.).

1. waitAfter being left
2. waitto stand at room temperature overnight
3. extractionextracted into diethyl ether
4. washThe ether extracts were washed with water
5. dry with materialdried over magnesium sulphate
6. concentrationconcentrated
7. customto give a pink solid which
8. washwas washed with petrol and air
9. customdried