Sodium Carbonate → HCID 15029611, compound

Participants

Reaction Steps

To a solution of 1-(1-phenylsulfinyl-2-formylaminoethyl)-2-methoxynaphthalene (3534 mg, 10 mmol) in toluene (60 ml) is added sodium carbonate (1060 mg, 10 mmol) and the mixture heated at reflux for 6 h. Then the mixture is filtered after cooling and the filtrate concentrated in vacuo. The residue is subjected to column chromatography over silica gel using as eluant cyclohexane/ethyl acetate (1:1) to give pure title compound with m.p. 160°-2° C., in 90% yield (1850 mg).

Provenance & Evidence